Introduction
The purpose of this study is to see how denosumab affects pain in individuals with fibrous dysplasia (FD). If you qualify and agree to participate in the study, you will be given denosumab by subcutaneous injection eight times over a 5-month period. You will be asked to come to the NIH Clinical Center for six visits over a 26-month period. During these visits you will be asked to participate in several tests and procedures, including a pain-related questionnaire, as described in the protocol consent.
Questionnaire: You will be asked to complete a questionnaire using a computer (or a paper version if you prefer written material or if the computer version is not available). It should take you less than an hour to complete the questionnaire. The questionnaire will be completed at the following protocol visits:
- Baseline (Visit 0)
- Follow-up visits at months 3, 6, 9, 14, 26
The questionnaire is:
- Wisconsin Brief Pain Inventory
To get started with the Questionnaires:
- Navigate through the menu to learn more about the study.
- Log in to the application and fill out questionnaires.
Please contact us if you have any questions or concerns.